Hepatic Resection and Prognosis for Patients with Single Hepatocellular Carcinoma Larger than 5

Other Titles
5 cm 이상의 간세포암 환자의 수술 후 예후 및 예후에 영향을 끼치는 인자
Authors
노지현
Issue Date
2015-06
Awarded Date
2015
Abstract
This study aimed to determine the clinicopathological factors that influence the prognosis of hepatic resection for HCC larger than 5 cm. Of 421 patients surgically resected HCCs, One hundred-fourteen patients (27.1%) had single HCC larger than 5 cm. Clinical features and factors influencing the outcome of these patients were retrospectively analyzed. The disease free survival and overall survival rate at 5 years was 29% and 43%. Multivariate analysis showed that the presence of microvascular invasion or macrovascular invasion, positive hepatitis B, and elevated PIVKA-II were the independent factor of worse outcome of disease free-survival rates in single HCC larger than 5 cm. In conclusion, hepatic resection is a feasible treatment for single HCC larger than 5 cm. Long term outcome was significantly influenced by the presence of micro- or macrovascular invasion, positive hepatitis B, and elevated PIVKA-II.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/11349
Appears in Collections:
3. 학위논문 > 1. School of Medicine (의과대학) > 석사
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http://dcollection.kmu.ac.kr//jsp/common/DcLoOrgPer.jsp?sItemId=000000051666
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