악성 섬유 조직구종

Other Titles
Malignant Fibrous Histiocytoma
Authors
권건영장은숙정재홍
Department
Dept. of Pathology (병리학)
Issue Date
1983
Citation
Keimyung Medical Journal, Vol.2(2) : 199-207, 1983
Abstract
Malignant Fibrous Histiocytoma (MFH) has become a well known malignant tumor of soft tissue since its description by O'Brien and Stout, and Stout and Lattes proposed as having a common origin from the tissue histiocyte, but there are different opinion that MFH is a neoplasm of undifferentiated mesenchymal cell with binary differentiation into histiocytoid and fibroblastic cells. Irrespective of its precise histogenesis, the tumor contains both fibroblast-like and histiocyte-like cells in varying proportions, accounting in part for its broad morphologic spectrum. The major microscopic characteristics include fibrogenic areas with spindle cells(fibroblast-like) arranged in a focal storiform pattern, clusters or sheets of histiocyte-like cells, benign and malignant giant cells, foam cells, inflammatory cells, scattered mitotic figures are frequently observed. This report presents a case of malignant fibrous histiocytoma arising in the previous laparotomy scar of low abdominal wall, where had been previously irradiated, of 39-year-old female patient who had had history of total abdominal hysterectomy with left salpingo-oophorectomy for cervical carcinoma on February 24, 1977’ radiation therapy after hysterectomy, right salpingo-oophorectomy for infiltrating papillary carcinoma of right ovary on April 18,1978, and after that Co therapy for 27 days, total 5400 rad, till June 15, 1978,and right hemicolectomy with ileo-colostomy for postoperative intestinal obstruction on November 11, 1978. It is our aim in this report to discuss histogenesis and to emphasize on the development of prognostic criteria of MFH.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14328
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
2. Keimyung Medical Journal (계명의대 학술지) > 1983
Keimyung Author(s)
권건영; 장은숙; 정재홍
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