사염화탄소 투여로 인한 간세포 상해와 간내 미세혈관계의 변화에 대한 주사전자현미경적 관찰

Other Titles
Scanning electron microscopic observations on the hepatocytes and intrahepatic microcirculation of the rat treated with carbon tetrachloride
Authors
채종민
Department
Dept. of Pathology (병리학)
Issue Date
1986
Citation
Keimyung Medical Journal, Vol.5(2) : 204-211, 1986
Abstract
Intracellular structures of hepatocytcs and the hepatic microcirculation were studied \n rats intoxicated with carbon tetrachloride by scanning electron microscopy. Liver tissues were treated by the DMSO cracking method and aldehyde-prefix osmium-DMSO-osmium method. A rapid, easy and reproducible method to prepare plastic corrosion casts of the hepatic microcirculation employed Mercox CL-2B. The hepatocytes around the portal tracts showed minimal abnormalities. However, swollen foamy hepatocytes in intermediate zone and central zone had numerous vesicles and vacuoles, which correspond to dilated cistemae of rough endoplasmic reticula (RERj and fat droplets observed by transmission electron microscopy and aldehyde prefix O-D-O method. And also, disorder of intrahepatic microcirculation was obsorved U\ he irregr/lar-shaped sinusoids and distended space of Disse in acute hepatic injury. This abnormal microcirculation was wt'!] demonstrated three-dimensionally by scanning clcctron microscopy of corrcsioii easts.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14442
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
2. Keimyung Medical Journal (계명의대 학술지) > 1986
Keimyung Author(s)
채종민
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