육아조직의 fibronectin의 면역 조직학적 검색

Other Titles
Immunohistologfical Demonstration of Fibronectin in Human Granulation Tissues
Authors
이상숙정재홍박준식
Department
Dept. of Pathology (병리학)
Issue Date
1987
Citation
Keimyung Medical Journal, Vol.6(1) : 60-66, 1987
Abstract
This study describes the distribution of fibronectin and its association with reticulin fibers (type Ⅲ collagen) in incisional wounds and previous biopsy sites of randomly sampled patients. The specimens were examined using immunofluorescence and immunoperoxidase to localize affinity-purified antibodies to fibronectin. Tissue samples were also stained with hematoxylin and eosin, and reticulum stain. Fibronectin was observed in the matrix surrounding individual fibroblasts and codistributed with reticulin fibers in early granulation tissue. Dense fibrillar networks of fibronectin and fibroblasts, giving the granulation tissue a highly stuctured and organized appearance. When the collagen had matured into bundles, fibronection dimimished or disappeared. These findings suggest that fibronectin may be important by functioning as a primary matrix for organization of the collagenous connective tissue during the tissue repair process.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14461
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
2. Keimyung Medical Journal (계명의대 학술지) > 1987
Keimyung Author(s)
이상숙; 정재홍
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