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육아조직의 fibronectin의 면역 조직학적 검색

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Affiliated Author(s)
이상숙정재홍
Alternative Author(s)
Lee, Sang SookChung, Chai Hong
Journal Title
Keimyung Medical Journal
Issued Date
1987
Abstract
This study describes the distribution of fibronectin and its association with reticulin fibers (type Ⅲ collagen) in incisional wounds and previous biopsy sites of randomly sampled patients. The specimens were examined using immunofluorescence and immunoperoxidase to localize affinity-purified antibodies to fibronectin. Tissue samples were also stained with hematoxylin and eosin, and reticulum stain. Fibronectin was observed in the matrix surrounding individual fibroblasts and codistributed with reticulin fibers in early granulation tissue. Dense fibrillar networks of fibronectin and fibroblasts, giving the granulation tissue a highly stuctured and organized appearance. When the collagen had matured into bundles, fibronection dimimished or disappeared. These findings suggest that fibronectin may be important by functioning as a primary matrix for organization of the collagenous connective tissue during the tissue repair process.
Alternative Title
Immunohistologfical Demonstration of Fibronectin in Human Granulation Tissues
Department
Dept. of Pathology (병리학)
Publisher
Keimyung University School of Medicine
Citation
이상숙 et al. (1987). 육아조직의 fibronectin의 면역 조직학적 검색. Keimyung Medical Journal, 6(1), 60–66.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/14461
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 1987
1. School of Medicine (의과대학) > Dept. of Pathology (병리학)
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