수종 피부질환에서 회상 항원에 의한 피부 지연 과민 반응의 비교 연구

Abstract

To assess cell-mediated immunity, We measured delayed cutaneous hypersensitivity by Multi-test® CMI in 108 cases including 20 cases of control, 25 cases of atopic dermatitis, 25 cases of wart, 25 cases of recurrent pyoderma and 13 cases of lymphoma. The results were obtained as follows: 1) Sum of average diameter of positive antigens was 18.86mm in atopic dermatitis, 20.5mm in wart, 25.7mm in pyoderma, 16.15mm in lymphoma and 21.6mm in control. There was no stass tistically significant difference between control and dermatoses. 2) Number of positive antigens was 3.4 in atopic dermatitis, 3.6 in wart, 4.4 in pyoderma, 2.6 in lymphoma and 4.1 in control. There were stastistically significant differences between lymphoma and four other groups(p<0.05). 3) The rate of anergy was 12% in atopic dermatitis and Zero % in four other groups. The rate of hypoergy was 24% in atopic dermatitis and wart, 16% in pyoderma, 62% in lymphoma and Zero % in control. 4) Antigen with highest response was diphtheria (76%) in atopic dermatitis, tuberculin (92%) in wart, diphtheria (80%) in pyoderma, tuberculin (100%) in lymphoma and tuberculin (100%) in control. Antigen with lowest response was trichophyton (8%) in atopic dermatitis, trichophyton (16%) in wart, trichophyton (28%) in pyoderma, diphtheria (15%) in lymphoma and tetanus (10%) in control. 5) Antigen acquired highest average score was tuberculin (6.1mm) in atopic dermatities, tuberculin (8.1MM) in wart, streptococcus (3.6mm) in pyoderma, tetanus (3.0mm) in lymphoma and tetanus (2.0mm) in control. 6) Average score of total antigens with positive response was 4.8mm in atopic dermatitis, 5.0 mm in wart, 5.7mm in pyoderma, 5.9mm in lymphoma and 4.4mm in control. 7) The rate of false positive reaction to 70% W/V glycerin was 2.8% totally.