흰쥐 재생간의 Glutathione S-Transferase 및 Glutathione Reductase의 활성치

Abstract

Changes in the activities of the following enzymes have been studied over a period of ten days after 70% (median and left lateral loves) partial hepatectomy in rats: cytosolic, mitochondrial and microsomal glutathione S-transferase, cytosolic glutathione reductase and cvtosolic glutathione peroxidase of regenerating liver. The activity of cytosolic glutathione S-transferase in the regenerating rat liver significantly diminished between the second and sixth days after the partial hepatectomy and that of mitochondrial glutathione S-transferase slightly decreased between the second and the thrid days after operation. However, the microsomal glutathion S-transferase activity in the regenerating rat liver showed a slight increase between the thrid and sixth days after operation. The cytosolic glutathione reductase activity in the regenerating rat liver slightly decreased between the first and thrid days after operation and the cytosolic glutathione peroxidase activity in the regenerating rat liver had a significant diminution between the second and the tenth days after the partial hepatectomy.