Keimyung Medical Journal, Vol.8(2) : 239-247, 1989
The results of orthotopic liver transplantation have improved since the introduction of cyclosporine into clinical transplantation. Among the other factors that contribute to raise the success rate of liver transplantation, standardization of surgical technique in donor and recipient and better uderstand of physiologic changes during and after anhepatic period are most important. Overall 1 year survival of adult and child are more than 70% recently and the results of some inborn error disease are much better. Because of these recent advances in iver transplantation, the list of absolute contranindications has progressively declined and the list of relative contraindications has expaned. Though the procurement of organs form heart beating donor is not possible in our country currently, every effort should be made to get the brain death by law and to improve the skill of transplantation. Social attitude about orhan donation, financial support by medical insurance, education and practicing of donor and recipient surgeon, anesthesiologist and immunologist are other problems we have to solve before we perform the liver transplantation.