유두상 및 충실성 상피종양: 1례보고와 전자현미경적 소견

Abstract

A case of papillary and solid epithelial neoplasm of the pancreas occured in 64-year-old woman without detectable symptoms was reported and the tumor was found incidentally on CT scanning work up for staging of known cervical carcinoma of the uterus. Distal pancreatectomy with splenectomy and radical hysterectomy were done. The tumor in the pancreas was large (10.4 X 7.5cm) and multilohulated, and showed good encapsulation with hemorrhagic center and pale homogenous yellowish white periphery on cut surface. Microscopically, the tumor was characterized by distinct papillary and solid pattern with microcystic change in areas. Most pancreatic carcinoma is high grade malignancy with a five-year survival of less than 5%, but papillary and solid epithelial neoplasm is potentially curable by surgical resection. Ultrastructurally, neoplastic cells contained a round to ovoid or indented nuclei with eccentric nucleoli and abundant cytoplasm with many mitochondria and some electron dense secretory granules.