만성 대동맥판 폐쇄부전증 환자에서 대동맥판 치환술후 좌심실 용적 및 심전도 변화

Abstract

Left ventricular(LV) hypertrophy is correlated with left ventricular myocardial mass, which occurs after long-standing LV over-loading. It is expected that surgical correction of chronic aortic regurgitation(AR) changes LV loading and then come changes in the LV function, dimension and myocardial mass. Serial electrocardiographic, echocardiographic LV studies were performed in 25 patients before and after aortic valve replacement(AVR) for chronic AR. Electrocariographic voltages were reduced significantly in 3 months after AVR(from 58.13±29.44 to 44.73±13.97(mm), p<0.05). Left ventricular systolic dimension was lessened markedly in the first 3 months after operation (from 4.55±105 to 3.38＋0.04(cm), p<0.05), but diastolic dimension was changed in the first 7 days(from 6.90±1.18 to 5.34±0.96(cm), p<0.05) The thickness of interventrcular septum and LV posterior wall increased after operation but they were not significant statistically. Ejection fraction decreased in the first 7 days after AVR(to 48.88±15.67(%), P<0.05), after then recovered as in the preoperative state. Muscle cross-sectional area was reduced at early post operative period(from 27.38±6.74 to 24.26±5.60(cm²), p<0.05) and increased thereafter. Thus, successful AVR for chronic AR results in the normalization of LV function and a decrease in ventricula₁ hypertrophy, while these changes in the LV function and dimension occur in early postop period.