Keimyung Medical Journal, Vol.9(3) : 351-354, 1990
Acute febrile neutrophilic dermatosis, which was introduced to the dermatologic literature by Sweet in 1964, is characterized by persistent higt fever and preceding upper respiratory infection like symptom, polymorphonuclear leukocytosis in the peripheral blood, raised painful plaque on the face, neck and limbs, histologically a dense dermal infilteration with polymorphonuclear leukocytosis, dramatic reponse to corticosteroids, and the absence of scarring. A 41 year-old female who had suffered from malaise, arthragia, upper respiratory tract infection like symptoms one month before the each episode of the cutaneous manifestation. Erythematous, well demarcated, slight scaly plaque appeared on the face with tendency of recurrences. Histologically a dense inflammatory cell infilteration, composed predominantly of polymorphonuclear leukocyte, lymphocytes and histiocytes were seen in dermis. The skin lesion and general symptoms were well controlled with orally administered corticosteroid.