Keimyung Medical Journal, Vol.9(3) : 355-359, 1990
A neurilemmoma is a relatively uncommon tumor of the nerve sheath and almost never in malignant form. It is a slow-growing, encapsulated nerve tumor. Benign neurilemmoma occur commonly in the cranial acoustic nerves, but can occur on the flexor surfaces of the upper and lower limbs. There is no appreciable sex predilection, and most cases are seen in adults past the age of 30 years. The tumor has been seen to arise in major nerves and nerve branches, including the posterior tibial nerve, peroneal nerve, and femoral nerve. Common differential diagnoses are ganglion, lipoma, neuroma, and hemangioma. Symptoms most often are a palpable mass, usually tender to palpatioin. A history of a localized area of swelling that increases in size and firmness over a period of several years is usual. Hitsologically, the tumor is composed of antoni type A and B tissue. In Antoni type A tissue, there are interlacing bundles of spindle-shaped cells arranged in a compact fashion with a pallisading of cell uunuclei. Antoni type B tissue exhibits the same type of cells loosely arranged with intervening collagen fibers. The tumor usually is located in deep tissue and rarely is just under the epidermis. And so we represents 3 cases of intradermal neurilemmoma in our department of dermatology.