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Virus Associated Hemophagocytic Syndrome 3례

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Author(s)
김준식서은숙강진무전동석
Alternative Author(s)
Kim, Joon SikSuh, Eun SookKang, Chin MooJeon, Dong Seok
Publication Year
1990
Keyword
Virus associated hemophagocytic syndrome
Abstract
Virus associated hemophagocytic syndrome is characterized by a benign generalized histiocytic proliferation with marked hemophagocytosis associated with systemic viral infectioin. The syndrome is a non-neoplastic, potentially reversible process and manifested fever, severe constitutional symptoms, hepatosplenomegaly, and lymphadenopathy, and characterized by laboratory findings of pancytopenia, hemophagocytosis and abnormal liver function test and coagulopathy. Immunosuppressive and cytotoxic therapy are contraindicated because of increasing risk of fatal outcome. The authors experienced three cases of virus associated hemophagocytic syndrome diagnosed by clinical features, bone marrow aspiration and lymph node biopsy. All cases had higt fever, hepatosplenomegaly and lymphoadenopathy and showed granulocytopenia in peripheral blood and phagocytized histiocytes in bone marrow. The brief review of the literatures was made.
Alternative Title
3 Cases of Virus
Associated Hemophagocytic Syndrome
Department
Dept. of Pediatrics (소아청소년학)
Dept. of Laboratory Medicine (진단검사의학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.9(3) : 369-379, 1990
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/14648
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