나환자의 혈청 과산화 지질

Abstract

Lipid peroxide is metabolic products of unsaturated fatty acid which functions, in vivo, are detoxification, drug metabolism, production of prostaglandins and microcidal action. If lipid peroxide increase in serum which causes variable metabolic disorders by impairement of organ cell membranes. But several enzymatic systems prevent high accumulations of lipid peroxide in serum. In this study, we have examined serum lipid peroxide conentration by using Yagi's method in 31 lepromatous leprosy patients and 11 tuberculoid leprosy patients. As normal controls, 22 healthy persons have been selected. As the results, Values of lipid perxide in leprosy patients superior to normal controls statistically(The values are significant only in lepromatous leprosy, not significant in tuberculoid leprosy patients.) We also found that sex, age, duration of disease had not affected the lipid peroxide levels. These results suggested that the type and severity of leprosy may be related the level of lipid peroxide. Now we present a paper, serum lipid peroxide in leprosy patients, with references.