Dept. of Internal Medicine (내과학); Dept. of Pathology (병리학); Institute for Medical Science (의과학 연구소)
Keimyung Medical Journal, Vol.17(4) : 542-548, 1998
The existence of gastric neuroendocrine carcinomas had been scarcely recognized. When present, the correct diagnosis is seldom made before surgery. The recognition of these tumors can be problematic for the pathologist. Some of these tumors have "small cell" appearance by light microscopic examination, but others only be called "poorly differentiated carcinoma". But tremendous advances in immunohistochemistry in the last 15 years have yielded powerful tools to the pathologist in diagnosing these tumors.
We experienced a case of neuroendocrine carcinoma of the stomach. The patient was a 67-year-old male and visited our hospital with epigastric pain. Subtotally resected stomach showed 3.5×4×5cm sized ulcerated tumor that was located at lesser curvature. Final diagnosis was neuroendocrine carcinoma, which stained positively for synaptophysin immunohistochemically.
Herein, we report a case of neuroendocrine carcinoma of stomach and review the literature.