Dept. of Nuclear Medicine (핵의학); Dept. of Internal Medicine (내과학); Institute for Medical Science (의과학 연구소)
Keimyung Medical Journal, Vol.18(1) : 134-145, 1999
Purpose : To evaluate prospectively the possibility of 99m Tc-MDP bone scan to detect early involvement of peripheral joint in rheumatic arthritis. Materials and Methods : 588 joints in 42 patients with rheumatic arthritis, whole body bone scan with 99m Tc-MDP and static bone scan of multiple joints of extremities(Wrist & Ankle) were done. Additionally. in 24 patients with positive rheumatic factor is compared. Results : The overall sensitivity and specificity of bone scan based on physical findings are 76.2% and 85.2%, respectively. The sensitivity and specificity of radiographic finding based on physical findings are 37. 6% and 84%, respectively.
In 24 patients with positive rheumatic factor, the sensitivity and specificity of bone scan based on physical findings are 71.7% and 84%, respectively. The sensitivity and specificity of radiographic finding based on physical findings are 54.5% and 87.4% respectively.
Conclusion: The bone scintigraphy is more sensitive than radiograph, may antedate the development of physical finding, regardness of positive rheumatic factor. We conclude that bone scintigraphy with 99m Tc-MDP is a valuable tool in the prediction of early joint involvement and evaluation of rheumatic arthritic activity in rheumatic arthritis.