난치성 측두엽간질의 발작기 국소뇌혈류 SPECT

Other Titles
Ictal rCBF SPECT in refractory temporal lobe epilepsy
Authors
전석길김지언류종걸손은익김순이상도
Department
Dept. of Nuclear Medicine (핵의학); Dept. of Neurology (신경과학); Dept. of Neurosurgery (신경외과학); Institute for Medical Science (의과학 연구소)
Issue Date
1999
Citation
Keimyung Medical Journal, Vol.18(4) : 491-500, 1999
Abstract
Refractory temporal lobe epilepsy is a disease of non-response to medical treatment, and the surgical resection of the epileptic focus is a treatment of choice. The ictal regional cerebral blood flow(rCBF) SPECT with Tc-99m ECD was done preperatively in ten refractory temporal lobe epilepsy patients. Engel's surgical outcome of one year after surgical resection of epileptic focus were analysed with ictal rCBF SPECT findings. Tc-99m ECD were labeled anticipatively, and placed in patient's bed of the patient monitoring room, and were injected within 7 seconds of seizure onset. Seven interictal rCBF SPECT and six MRI were also performed. There was positive findings in six cases, of which five were increased rCBF, and remaining one revealed decreased rCBF at epileptic focus, and IA to ⅡB of Engel's surgical outcome were noticed. One case of four normal ictal rCBF SPECT showed decreased rCBF in interictal rCBF SPECT. Four cases of seven interictal rCBF SPECT showed normal findings. Five of nine MRI shows normal findings, in which abnormal ictal rCBF SPECT were noticed. As a conclusion, ictal rCBF SPECT could help to find out epileptic focus in refractory temporal lobe epilepsy.
Keywords
EpilepsyTemporal lobeIctal phaseRCBF SPECTTc-99m ECD
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15173
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Neurology (신경과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
1. Journal Papers (연구논문) > 3. Research Institutues (연구소) > Institute for Medical Science (의과학연구소)
2. Keimyung Medical Journal (계명의대 학술지) > 1999
Keimyung Author(s)
전석길; 이상도; 김지언; 손은익
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