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B형 전림프구성 백혈병 1례

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Author(s)
윤상미이홍석박근규전동석송홍석
Publication Year
1999
Keyword
B-prolymphocytic leukemiaCombination chemotherapy
Abstract
Prolymphocytic leukemia(PLL) first described by Galton and colleagues in 1974, is a distinct clinicopathologic variant of chronic lymphocytic leukemia. It is characterized by marked lymphocytosis, massive splenomegaly, minimal lymphadenopathy, and poor prognosis. The clinical course of PLL is generally brief, the median survival in Galton's original series was 4 months. We experienced a case of B-prolymphocytic leukemia. The patient was a 64 year-old man who presented with splenomegaly, marked leukocytosis and 65% of characteristic prolymphocytes in the peripheral blood. We report a case of PLL with a prolonged course after combination chemotherapy with daunorubicin, L-asparaginase, vincristine, prednisolone, and methotrexate.
Alternative Title
A Case of B-Cell
Prolymphocytic Leukemia
Department
Dept. of Internal Medicine (내과학)
Dept. of Laboratory Medicine (진단검사의학)
Institute of Medical Cytogenetics (유전의학연구소)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.18(4) : 548-554, 1999
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15180
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