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암 진단지표로서 MAGE의 특성

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Affiliated Author(s)
박종욱
Alternative Author(s)
Park, Jong Wook
Journal Title
Keimyung Medical Journal
Issued Date
2003
Keyword
Cancer diagnosis markerMelanoma antigen gene
Abstract
The human MAGE A family encodes products that can be recognized by autologous cytotoxic T cells. Because MAGE genes are silent in most normal tissues except testis but are activated in a variety of neoplastic lesions, MAGE antigens represent ideal targets for cancer diagnosis and immunotherapy. MAGA A family consists of 12 subtypes, and there are high DNA homology between subtypes. Here, I discussed the importance of MAGE as cancer diagnosis marker and molecular methods for the detection of several MAGE subtypes together by RT-PCR using common primers.
Alternative Title
Characteristics of
MAGE as Cancer Diagnosis Marker
Department
Dept. of Immunology (면역학)
Publisher
Keimyung University School of Medicine
Citation
박종욱. (2003). 암 진단지표로서 MAGE의 특성. Keimyung Medical Journal, 22(별호), 125–130.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15311
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2003
1. School of Medicine (의과대학) > Dept. of Immunology (면역학)
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