골다공증성 척추압박골절에 대한 Polymethylmethacrylate 척추체성형술의 효과

Abstract

This study was performed to assess the feasibility, safety, and clinical outcome of percutaneous transpedicular polymethylmethacrylate vertebroplasty (PTPV) for the treatment of vertebral compression fractures causing refractory pain. The clinical and rediological data of 295 vertebrae in 218 patients, who underwent PTPV for vertebral compression fractures between August 2000 and June 2004, were retrospectively reviewed. Imaging and clinical features were analyzed, including the age, sex, bone marrow density (BMD) score, symptom duration, number of collapsed vertebra, compression grade of vertebra, leakage of bone cement, volume of injected bone cement, vertebroplasty complication, and clinical outcome. The mean age was 69.7 yaers (58-87 years). The average BMD score was-3.62, indicating severe osteoporosis. The mean duration of follow-up was 7.3 months (3-14 months). Symptoms were improved in 81.2%, worse in 0.9% and the same in 17.9%. Extrusion of polymethylmethacrylate cement beyond the confines of the vertebral body was observed in 34 cases (11.5%), but set in no serious complications. PTPV is safe and feasible treatment for patients with vertebral compression fractures and provides significant early relief in a high percentage of patients with refractory pain and prevents vertebral collapse.