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신세포암에서 예후 인자로 혈소판 증가증, 적혈구침강속도 및 C반응단백의 비교

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Affiliated Author(s)
장혁수김병훈박철희김천일
Alternative Author(s)
Chang, Hyuk SooKim, Byung HoonPark, Choal HeeKim, Chun Il
Journal Title
Keimyung Medical Journal
Issued Date
2010
Keyword
C-reactive proteinPrognosisRenal cell carcinoma
Abstract
The purpose of this study was to assess relationship between the prognosis of patients and the degree of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and thrombocytosis on the patients who underwent radical nephrectomy. The subject of study was 65 patients who underwent radical nephrectomy with Renal cell carcinoma (RCC) and whose level of ESR, CRP and thrombocytosis were measured at the time of making diagnosis. The study was conducted by classifying above ESR 20 mm/hr, CRP 0.5 mg/dL and thrombocytosis 350,000/uL as "increased
group" and below these as "normal group". The tumor size, cellular type, pathologic stage, nuclear grade and distant metastasis were compared between two groups. The thrombocytosis and ESR were not found significant as prognostic factors in the multivariate analysis, but CRP was associated with cellular type (p=0.022), high degree of nuclear grade (p=0.006) and distant metastasis (p=0.001) and also was a significantly independent prognosis factor (p=0.020) in the multivariate analysis. In conclusion, the measurement of CRP at the time of making diagnosis will be very helpful for the estimation of prognosis in patients with RCC.
Alternative Title
Comparison of Thrombocytosis, Erythrocyte Sedimentation Rate and C-reactive Protein as
Prognostic Factors in Patients with Renal Cell Carcinoma
Department
Dept. of Urology (비뇨의학)
Publisher
Keimyung University School of Medicine
Citation
서경원 et al. (2010). 신세포암에서 예후 인자로 혈소판 증가증, 적혈구침강속도 및 C반응단백의 비교. Keimyung Medical Journal, 29(1), 35–43.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15490
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2010
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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