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4 cm 이하의 임상 T1a병기 신세포암에서 크기에 따른 임상 및 병리적 소견

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Affiliated Author(s)
김병훈
Alternative Author(s)
Kim, Byung Hoon
Journal Title
Keimyung Medical Journal
Issued Date
2011
Keyword
Computed tomographyRenal cell carcinomaRenal tumor
Abstract
Purpose : A small renal cell carcinoma (RCC) detected incidentally without symptom is increased
due to the generalization of the ultrasonographic and computed tomography. We evaluated the
relationship of pathologic T stage, nuclear grade, histology and presence or absence metastasis
according to size of less than 4cm sized RCC. Materials and Methods : We analyzed the medical
records and pathology reports of 97 patients with less than 4 cm RCC in preoperative imaging studies who underwent radical nephrectomy or partial nephrectomy from January 1996 to December 2008. The size of the patients were divided into 2 groups, according to size of tumor less than 3.1 cm groups and 3.1-4 cm groups. The pathological T stage, histology, nuclear grade, and metastasis of each groups were investigated. Pathologic T stage were classified according to American Joint Committe on Cancer 2002, and the nuclear grade were assessde by the Fuhrman classification. Results : Less than 3.1 cm groups (A) and 3.1-4 cm (B) groups divided according to the size of RCC were 68 cases (70%) and 29 cases (30%), respectively. When pathologic T
stage for each groups were divided into pT1 and pT3, pT1 were 65 cases (95.6%), 21 cases (72.4%), and pT3 were 3 cases (4.4%), 8 cases (27.6%), respectively (Table 2) (p<0.05). When nuclear grade of each groups were divided into the low grade (grade I, II) and the high grade (III, IV), the low grade were 62 cases (81.2%), 19 cases (65.5%), and the high grade were 6 cases
(8.8%), 10 cases (34.5%), respectively (Table 2) (p<0.05). When histology of each groups were
divided into conventional and non-conventional type, conventional type were 51 cases (75%), 25
cases (86.2%), and non-conventional type were 17 cases (25%), 4 cases (13.8%), respectively
(Table 3) (p>0.05). All groups had no metastases at diagnosis. Conclusions : Though size of
RCC was less than 4 cm in size, the rates of pT3 stage and high nuclear grade (grade III, IV) was
higher in larger tumor size. Thus the size of renal tumor is small, postoperative follow-up was
practiced more accurately because difference of malignancy grade was detected by renal tumor size.
Alternative Title
Clinical and Pathological Features According to Tumor Size in Patients with Clinical T1a Renal Cell Carcinoma
Department
Dept. of Urology (비뇨의학)
Publisher
Keimyung University School of Medicine
Citation
김형종 and 김병훈. (2011). 4 cm 이하의 임상 T1a병기 신세포암에서 크기에 따른 임상 및 병리적 소견. Keimyung Medical Journal, 30(1), 67–73.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15520
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2011
1. School of Medicine (의과대학) > Dept. of Urology (비뇨의학)
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