A Case of Amiodarone Hepatotoxicity in Patient with Atrial Fibrillation

Abstract

Amiodarone has an important drug in treatment for arrhythmia, but cannot be overlooked in practical medicine. Among the side effects associated with iodine contained in amiodarone, thyroid dysfunction is well known, but steatohepatitis is rarely reported. We described a 65-year-old female, with history of amiodarone treatment for atrial fibrillation, presenting with dyspnea and hand-tremor. Computed tomography (CT) revealed a high-density of liver parenchyma on nonenhanced imaging which was compatible with the hepatotoxicity as of iodine accumulation. Thus, we report an unusual but important presentation of amiodarone hepatotoxicity.