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경피적 척추성형술 후 추가 골절발생의 임상적 분석

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Affiliated Author(s)
김인수
Alternative Author(s)
Kim, In Soo
Journal Title
Keimyung Medical Journal
Issued Date
2012
Keyword
Compression fractureOsteoporosisVertebroplasty
Abstract
Objective: This study aims to investigate the incidence and risk factors of subsequent vertebral
fracture after percutaneous vertebroplasty (PV) with polymethylmethacrylate (PMMA) in patients with osteoporotic vertebral compression fractures (OVCF). Methods: This study retrospectively reviewed 188 patients (148 women and 40 men) who underwent PV for the treatment of OVCF at a single institute between March 2005 and January 2011. Patients who
returned with new fracture after initial successful PV were evaluated by repeat MR imaging. This study analyzed the incidence and risk factors of subsequent vertebral fracture, including BMI, Bone mineral density(BMD), presence of diabetes, smoking, use of bisphosphonates, cement volume, cement leakage into the disc. Data were also analyzed according to level of fracture, adjacent fracture or non-adjacent fracture, and we compared the risk factors. Results: Among 188 patients treated with PV, 32 patients (17%) experienced newly developed vertebral fractures during the follow-up period (28.84±11.92 months on the average). 32 subsequent
vertebral fractures were 17 adjacent level vertebral fractures and 15 non-adjacent level vertebral fractures. Subsequent vertebral fractures at the lumbar level (53.1%) were more frequent than those at thoracic level (46.9%). Smoking, diabetes mellitus, amount of PMMA, and bisphosphonate use did not correlate with the risk of subsequent fracture. BMD, BMI and intradiscal leakage of PMMA were the significant risk factors. Conclusion: The subsequent
vertebral fracture should be considered before PVA with PMMA. The cement leakage into the disc, low BMI and low BMD could increase the risk of subsequent fracture.
Alternative Title
Clinical Analysis of Subsequent Vertebral Fracture after Percutaneous Vertebroplasty
Department
Dept. of Neurosurgery (신경외과학)
Publisher
Keimyung University School of Medicine
Citation
김인수. (2012). 경피적 척추성형술 후 추가 골절발생의 임상적 분석. Keimyung Medical Journal, 31(1), 74–82.
Type
Article
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/15556
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2012
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
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