이식신에 발생한 결핵의 성공적인 치료 1례

Abstract

Tuberculosis is a significant opportunistic infection in transplant recipient and the incidence of tuberculosis in this population is much higher compared with the general population. Pulmonary tuberculosis is the most common site of tuberculosis, but renal allograft tuberculosis is very rare. Tuberculosis involving the renal allograft is a potential cause for graft dysfunction or loss, so early diagnosis and treatment is important. We report a case of the allograft kidney tuberculsosis, treated by anti-tuberculosis medication. A 46-year-old man had undergone his first kidney transplantation from living-related donor 17 years earlier. At two years post-transplantation, he diagnosed pulmonary tuberculosis and treated by anti-tuberculosis medication for six months. This allograft kidney was lost due to chronic rejection. He underwent a second transplantation from deceased donor at ten years earlier and received prophylaxis isoniazid for at a year. He diagnosed miliary tuberculosis with allograft kidney tuberculosis. He was treated by antituberculosis medication successfully and maintained his allograft kidney function.