An Intra-procedural Stent Thrombosis in a Prasugrel Resistant
Patient Treated with Ticagrelor
- Affiliated Author(s)
- 허승호; 조윤경; 박형섭; 윤혁준; 김형섭; 남창욱; 한성욱
- Alternative Author(s)
- Hur, Seung Ho; Cho, Yun Kyeong; Park, Hyoung Seob; Yoon, Hyuck Jun; Kim, Hyung Seop; Nam, Chang Wook; Han, Seong Wook
- Journal Title
- Keimyung Medical Journal
- Issued Date
- 2016
- Keyword
- Prasugrel resistance; Stent thrombosis; Ticagrelor
- Abstract
- Stent thromboses due to multifactorial causes including hypercoagulable
conditions and high on treatment platelet reactivity (HTPR), which means a
low response to anti-platelet therapy, especially clopidogrel. Prasugrel is a
third generation thienopyridine and inactive pro-drug requiring metabolic
activation in vivo, which improves the rate of HTPR with clopidogrel. This
drug is mostly effective, with a potent, fast, and consistent anti-platelet
action, but rare cases of inadequate platelet inhibition with prasugrel have
been reported. Here we describe the case of a 47-year-old man who
presented with a recurrent acute myocardial infarction and ST during an
intravascular ultrasound pullback and was resistant to prasugrel, was
successfully treated with ticagrelor.
- 공개 및 라이선스
-
- 파일 목록
-
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.