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칸디다 균혈증에 대한 중재가 항진균제 사용 및 안과 검진에 미치는 영향

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Author(s)
하나정현미리김현아류성열
Publication Year
2016
Keyword
CandidaCandidemiaEndophthalmitis
Abstract
Candidemia is increasing cause of mortality, especially in
intensive care unit patients. And Candida endophthalmitis,
developed with or without symptoms, has poor outcome. Prompt
use of antifungal agents and early diagnosis of Candida
endophthalmitis are clinically important to treat candidemia. In
this study, we compared clinical, microbiological, ophthalmological
characteristics and treatment outcomes whether infectious
disease (ID) specialists mediate candidemia or not in a tertiary
hospital by retrospective chart review. Group A includes
patients who had candidemia at least one time from January
2012 to July 2013, without ID specialists mediation. Group B
includes patients who had candidemia at least one time from
August 2013 to December 2014, with ID specialists surveillances
and mediations. We compared clinical manifestations of
candidemia, uses of antifungal agent, ophthalmologic evaluations
and treatment outcomes between two groups. In group A, rate
of ophthalmologic evaluations was 4.4% and mean duration was
64.60 hours from blood culture to use of antifungal agents. In
group B, the rate of ophthalmologic evaluations was 43.2% and
mean duration was 50.15 hours. There was no statistically
significant difference in clinical characteristics and 30-day
mortality between two groups. Increasing rate of ophthalmologic
evaluations and decreasing mean duration from blood culture to use of antifungal agents was shown in surveillance
and mediation group.
Department
Dept. of Internal Medicine (내과학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.35(2) : 98-104, 2016
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15707
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