항암치료 후 면역억제자에서 심한 임상 경과를 보인 수두 1례

Other Titles
Severe Chicken Pox in an Immunocompromised Host after Chemotherapy
Authors
정진웅권준일김성애류영욱
Department
Dept. of Dermatology (피부과학)
Issue Date
2016
Citation
Keimyung Medical Journal, Vol.35(2) : 147-152, 2016
Abstract
Chicken pox is highly contagious and occurs most often in childhood. In normal children, systemic symptoms are usually mild and serious complications are rare. But in adults, especially in immunocompromised patients, it is more likely to be associated with life-threatening complications such as pneumonia, encephalitis and sepsis. A 38-year-old woman was admitted due to headache, fever and multiple umbilicated vesicles on face, trunk and both extremities for 3 days. She underwent chemotherapy for the breast cancer 20 days prior to admission. Based on typical clinical presentation and skin biopsy, she was diagnosed with chicken pox. Despite 5 days of intensive intravenous antiviral therapy (Acyclovirⓡ 30 mg/kg/day), fever and headache continued and epigastric pain occurred. Finally, the patient was recovered from varicella after additional 7 days of antiviral therapy. Generally, old age or immunocompromised hosts have declined cellular immunity, so the incidence of chicken pox is higher and the clinical course is more severe. Herein, we report a case of chicken pox in the patient who underwent chemotherapy for breast cancer, requiring intensive treatment and close observation for systemic symptoms.
Keywords
AdultBreast cancerChemotherapyChicken pox
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15714
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2016
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
Keimyung Author(s)
김성애; 류영욱
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