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분만 유도를 위한 경구용과 경질용 Misoprostol의 비교

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Author(s)
배진곤신소진박준철권상훈조치흠이정호차순도윤성도김종인
Alternative Author(s)
Bae, Jin GonShin, So JinPark, Joon CheolKwon, Sang HoonCho, Chi HeumRhee, Jeong HoCha, Soon DoYoon, Sung DoKim, Jong In
Issued Date
2008
Keyword
Induction of laborMisoprostolOral or vaginal administration
Abstract
Recently, some studies reported that transvaginal misoprostol induced successful vaginal delivery. The aim of this study were to compare the efficacy and the safety between oral and vaginal administration of misoprostol for the induction of labor. Pregnant women who were hospitalized for the induction of labor from January 2004 to December 2006 at the Dong san Medical Center were included for the prospective randomized study. Subjects as a change in Bishop score of ≥3, Bishop score of ≥6 at 12 hours, or vaginal delivery after the insert placement. One hundred seventy-one women (Oral misoprostol group 85 women / Vaginal misoprostol group 86 women) completed the protocol. There were no statistically significant differences between the two groups in terms of a successful outcome (61.2% vs 67.4%; p=0.223) and the following mean time to vaginal delivery (13.3 hours vs 14.5 hours ; p=0.722). In addition, no differences were observed in the incidences of cesarean delivery, hyperstimulation syndrome, abnormal fetal heart tate patterns, and adverse neonatal outcomes. We concluded that both misoprostol administration routes were equally effective in achieving cervical ripening initiating labor, and achieving a successful vaginal delivery.
Alternative Title
Comparison between Oral and Vaginal Administration of Misoprostol for Induction of Labor
Department
Dept. of Obstetrics & Gynecology (산부인과학)
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.27(2) : 133-141, 2008
Type
Article
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/15927
Appears in Collections:
2. Keimyung Medical Journal (계명의대 학술지) > 2008
1. School of Medicine (의과대학) > Dept. of Obstetrics & Gynecology (산부인과학)
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