면역착색조영술 측정법에 의해 확인된 쯔쯔가무시 수막뇌염 2례

Abstract

Definite diagnosis is difficult in patient with tsutsugamushi disease involving neurological system. We report two cases of meningoencephalitis associated with tsutsugamushi disease confirmed by immunochromatographic assay. Two patients were transferred emergency room due to mental confusion during doxycycline medication under tentative diagnosis of tsutsugamushi disease. Neurological examination showed confusion with poor cooperation only. After confirmation of tsutsugamushi meningoencephalitis by immunochromatographic assay for cerebrospinal fluid, they continued doxycycline medication. After 3 days, their symptoms were completely subcided without any neurological sequelae.