Response to Gerlic et al.

Title
Response to Gerlic et al.
Authors
Seung-Soon ImStephen G. YoungManuela RaffatelluTimothy F. Osborne
Keimyung Author(s)
임승순
Department
Dept. of Physiology (생리학)
Issue Date
2014
Publisher
School of Medicine
Citation
Cell metabolism, Vol.19(3) : 346-347, 2014
Abstract
Gerlic et al. contacted us a few months ago regarding the concerns expressed in the accompanying letter. We have communicated with them about their observations relative to conclusions from our original paper (Im et al., 2011) and for the field moving forward. Based on their data, we performed a separate DNA sequence analysis of the Nlrp1a locus in our SREBP-1a-deficient (SREBP-1aDF) mice and confirmed that it is derived from the 129 strain. However, the issues raised by this observation are almost certainly more complicated than the tight linkage between the Srebf1 and Nlrp1a loci and the extent of backcrossing.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/17041
ISSN
1550-4131
Appears in Collections:
1. 연구논문 > 1. School of Medicine (의과대학) > Dept. of Physiology (생리학)
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