임상가검물에서 최근 6년간 분리한 대장균의 항균제내성의 추이

Title
임상가검물에서 최근 6년간 분리한 대장균의 항균제내성의 추이
Other Titles
Changes of Antimicrobial Resistance of Escherichia coli Isolated from Clinical Specimens During Recent 6 Years
Authors
서성일백성덕백원기박종욱최병길서민호Seong-Il SuhSung-Duk PaikWon-Ki BeakJong-Wook ParkByung-Kil ChoeMin-Ho Suh
Keimyung Author(s)
서성일; 백원기; 서민호; 박종욱; 최병길
Department
Dept. of Microbiology (미생물학); Dept. of Immunology (면역학); Institute for Medical Science (의과학연구소)
Keywords
Escherichia coli; Multiple drug resistance
Issue Date
1994
Publisher
School of Medicine
Citation
대한미생물학회 The Korean Society For Microblology, Vol.29(6) : 565-572, 1994
Abstract
Escherichia coli ranks very high among bacteria isolated from clinical specimens. From 1987 to 1992, E. coli isolated from various clinical specimens were tested for resistance to antimicrobial drugs. Most of the strains tested were susceptible to quinolone carboxylic acid compounds (QA), moxalactam (Mx), amikacin (Ak), and rifampin (Rf), but other drugs tested showed very low antimicrobial activities against the majority of strains. Especially, resistance frequency of EL coli against cephalothin, cefamandole, and gentamicin have been increased gradually during last 6 years. 90% MIC of drugs tested were very high except QA, Mx, Ak and Rf and over 50% of organisms multiflying resistance to 6 or more drugs were noted. Of importance has been the steadily increasing resistance of E. coli to many antibiotics from 1987 to present. However, reversal of these trends of antimicrobial resistance may result from more specifically directed choices of drugs for infectious diseases, reduction in the excessive uses of antibiotics, the use of more rational dosage regimens, and discontinuance of general and routine antibiotic prophylactic regimens in hospitals.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/23344
ISSN
0253-3162
Appears in Collections:
1. 연구논문 > 1. School of Medicine (의과대학) > Dept. of Microbiology (미생물학)
1. 연구논문 > 1. School of Medicine (의과대학) > Dept. of Immunology (면역학)
1. 연구논문 > 3. Researcher Institutues (부설연구소) > Institute for Medical Science (의과학연구소)
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