자궁경부암에 있어서 특이적 염색체변화와 flow cytometry에 의한 핵산 함량분석

Title
자궁경부암에 있어서 특이적 염색체변화와 flow cytometry에 의한 핵산 함량분석
Other Titles
Specific Cytogenetic Characteristics and DNA Content Analysis by Flow Cytometry in Cervical Cancer
Authors
장성익정용욱이인환최인장김대광
Keywords
Chromosome and DNA Content analysis
Issue Date
1990
Publisher
Keimyung University School of Medicine
Citation
Keimyung Medical Journal, Vol.9(2) : 184~190, 1990
Abstract
In order to understand the specific chromosomal changes and DNA content analysis by flow cytometry in cervical cancer of Korean women; firstly we investigated cervical cancer cell line. The chromosomal number of cervical cancer cell line was hyperdipolid and prominent numerical abnormalities were in trisomy 1; 2; 6; 12; 16; 17; 18; 20; 21; 22 and tetrasomy 2 Specific Structural rearrangements were deletion (on lp22; 2p21; 3p21; 3qll; 6q23; 7pl4; 7p21; lOpll; 22qll); translocation(3qll; lOpll); isochromosome (5q) and marker chromosome Common break points at bands lp22; 22qll give rise to the loss of cellular oncogene fgr; src-2; N-myc; rafl; myb; sis respectively
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/2643
Appears in Collections:
학술지 > 1990
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