Long-term Clinical Outcomes of Kidney Re-transplantation
- Affiliated Author(s)
- 박성배; 김형태; 박우영; 강성식; 한승엽; 진규복; 박의준; 조원현
- Alternative Author(s)
- Jin, Kyu Bok; Park, Sung Bae; Park, Woo Young; Han, Seung Yeup; Kang, Seong Sik; Cho, Won Hyun; Kim, Hyoung Tae; Park, Ui Jun
- Journal Title
- Tansplantation Proceedings
- ISSN
- 0041-1345
- Issued Date
- 2017
- Abstract
- Background. Kidney re-transplantation is commonly considered to have a higher
immunological risk than first kidney transplantation. Because of the organ shortage and
increasing waiting lists, long-term outcomes of kidney re-transplantation are being
studied. However, reports of re-transplantation outcomes are not common. We have
reported our 30 years of experience with second kidney transplantations.
Methods. Of 1210 kidney transplantations between November 1982 and August 2016
performed in our hospital, 105 were second kidney transplantations (2nd KT). Living
donor KT was 44; deceased donor KT was 61.
Results. Patient survival rates at 1, 5, and 10 years were 100%, 97.2%, and 90.7%, and
graft survival rates were 97.0%, 94.6%, and 71.5%, respectively. The leading cause of graft
failure in the 2nd KT was chronic rejection (60%). In addition, induction immunosuppressant,
maintenance immunosuppressant, delayed graft function, and graft survival time
at the 1st KT had a significant impact on graft survival time at the 2nd KT.
Conclusions. Reasonable results in both patient survival and graft survival rates were
found in the 2nd KT. Careful monitoring of immunologic risk is needed.
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