최근 포도알균화상피부증후군 환아에서 Methicillin-resistant Staphylococcus aureus 감염 경향과 항생제 사용에 관한 연구: 단일 기관 경험

Other Titles
Recent Trends in Methicillin-resistant Staphylococcus aureus Infection and Antibiotic Treatment in Staphylococcal Scalded Skin Syndrome in Patients in Childhood: A Single-center Study
Authors
조현재류영욱김성애
Department
Dept. of Dermatology (피부과학)
Issue Date
2017
Citation
대한피부과학회지, Vol.55(1) : 20-26, 2017
ISSN
0494-4739
Abstract
Background: Staphylococcal scalded skin syndrome (SSSS) is a blistering disease of superficial skin mediated by Staphylococcus aureus (S. aureus) exfoliative toxin. Generally, SSSS affects mainly infants and children younger than 5 years and has a good prognosis. However, an increasing number of cases of methicillin-resistant S. aureus (MRSA) have been reported recently. Objective: The purposes of this study were to evaluate the clinical features and course, to investigate the microbiological manifestations, and to perform antimicrobial susceptibility testing of SSSS among Korean children. Methods: From March 2003 to July 2016, a total of 141 children were included in this study. The patients were divided into two different groups according to time of onset of their disease: before or after September 2011. We retrospectively reviewed medical records, microbiological results, bacterial detection sites, and antimicrobial susceptibility tests of all participating children. The results of comparison between the two groups were evaluated using the chi-square test. Results: S. aureus infections were identified in all patients. Among all cultured S. aureus specimens, 63.1% (89/141) showed methicillin resistance. Beginning in September 2011, MRSA infection showed a significantly higher prevalence than that previously demonstrated (71.7% vs. 38.8%; p=0.0010). Moreover, MRSA infections were detected on the skin and neck and in the nose (each detected on 61, 41, and 18 occasions, respectively) with overlap observed in many cases. Conclusion: In conclusion, since the prevalence of MRSA infection has been gradually increasing in recent years, careful consideration is needed in the selection of antibiotics covering MRSA.
Keywords
Antimicrobial susceptibility testMethicillin-resistant Staphylococcus aureusStaphylococcal scalded skin syndrome
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/32877
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Dermatology (피부과학)
Keimyung Author(s)
김성애; 류영욱
Full Text
http://kiss.kstudy.com/thesis/thesis-view.asp?key=3494347
File in this Item
 사서에게 요청하기
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE