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Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults.

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Affiliated Author(s)
허승호
Alternative Author(s)
Hur, Seung Ho
Journal Title
Korean Circulation Journal
ISSN
1738-5520
Issued Date
2015
Keyword
Myocardial infarctionYoung adultPrognosis
Abstract
Background and Objectives: This study aims to investigate the clinical features, angiographic findings, and outcomes of younger Korean
ST-segment elevation myocardial infarction (STEMI) patients.
Subjects and Methods: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November
2005 to October 2010. The registered patients were divided into two groups; young age group (<65 years) and old age group (≥65 years).
Results: The young age group included 5281 patients (age, 53±7.8 years), and the old age group included 4896 patients (age, 74.3±6.5
years). Male gender, smoking, family history, dyslipidemia, and metabolic syndrome were more frequently observed in the young age group
than in the old age group (89.5% vs. 59.3%, p<0.001; 77.3% vs. 47.2%, p<0.001; 11% vs. 4.6%, p<0.001; 11.2% vs. 7.7%, p<0.001; 67.6% vs.
62.9%, p<0.001). Most of the young Korean adults with STEMI complained of typical chest pain (89.8%), and they had a shorter symptomto-
door time (12±53.2 hours vs. 17.3±132 hours, p=0.010). The young age group showed a favorable prognosis, which was represented by
the MACE, compared with the old age group at one month (1.8% vs. 2.8%, p=0.028), six months (6.8% vs. 8.2%, p<0.001), and twelve
months (10.1% vs. 11.9%, p=0.025). However, there was no significant difference in the adjusted MACE rate at one month {hazard ratio (HR)
0.95, 95% confidence interval (CI) 0.60-1.51, p=0.828} and twelve months (HR 0.86, 95% CI 0.68-1.10, p=0.233).
Conclusion: Younger Korean adults with STEMI have clinical outcomes similar to old aged patients, and therefore, they should be treated
intensively like the elderly patients.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Seung Hun Lee et al. (2015). Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults. Korean Circulation Journal, 45(4), 275–284. doi: 10.4070/kcj.2015.45.4.275
Type
Article
ISSN
1738-5520
DOI
10.4070/kcj.2015.45.4.275
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/32909
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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