Comparison of the microbiological characteristics and virulence factors of ST131 and non-ST131 clones among extended-spectrum β-lactamase-producing Escherichia coli causing bacteremia.
- Affiliated Author(s)
- 류성열; 김현아
- Alternative Author(s)
- Ryu, Seong Yeol; Kim, Hyun Ah
- Journal Title
- Diagnostic Microbiology and Infectious Disease.
- ISSN
- 0732-8893
- Issued Date
- 2016
- Keyword
- ESBL-producing Escherichia coli; Sequence type 131; Virulence factors
- Abstract
- We evaluated the molecular epidemiology and microbiological characteristics of extended-spectrum β-
lactamase–producing Escherichia coli (ESBL-EC) isolates that cause bacteremia in Korean hospitals, focusing especially
on ST131. Our data suggest that ST131 isolates possessedmore virulence traits and showedmoremultidrug
resistance patterns than non-ST131 isolates.Among CTX-M-15 producers, the frequency of serumresistancewas
significantly higher in ST131 than in non-ST131. As in other parts of the world, the ESBL-EC ST131 clone has
emerged and disseminated in both community and hospital settings in Korea, including in blood isolates in patients
with bacteremia.
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