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Simplified Radiographic Damage Index for Affected Joints in Chronic Gouty Arthritis

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Affiliated Author(s)
손창남
Alternative Author(s)
Son, Chang Nam
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934
Issued Date
2016
Keyword
GoutRadiographyBone ErosionReliability
Abstract
The aim of this study was to develop and validate a new radiographic damage scoring
method (DAmagE index of GoUt; DAEGU) in chronic gout using plain radiography. Two
independent observers scored foot x-rays from 15 patients with chronic gout according to
the DAEGU method and the modified Sharp/van der Heijde (SvdH) method. The 10
metatarsophalangeal (MTP) and 2 interphalangeal (IP) joints of the first toes of both feet
were scored to assess the degrees of erosion and joint space narrowing (JSN). The
intraobserver and interobserver reliabilities were analyzed by calculating the intraclass
correlation coefficient (ICC) and minimal detectable change (MDC). The correlation
between the DAEGU and SvdH methods was analyzed by calculating the Spearman’s rho
correlation coefficients and Kappa coefficients. The DAEGU method was found to be highly
reproducible (0.945-0.987 for the intraobserver and 0.993-0.996 for the interobserver ICC
values). The erosion, JSN, and total scores exhibited strong positive correlations between
the DAEGU and SvdH methods and also within each method (r = 0.860-0.969, P < 0.001
for all parameters). The DAEGU and SvdH methods were in very good agreement as
determined by Kappa coefficient analysis [0.732 (0.387-1.000) for erosion and 1.000
(1.000-1.000) for JSN]. In conclusion, this study revealed that DAEGU method was a
reliable and feasible tool in the assessment of radiographic damage in chronic gout. The
DAEGU method may provide a more easy assessment of structural damage in chronic gout
in the real clinical practice.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Chang-Nam Son et al. (2016). Simplified Radiographic Damage Index for Affected Joints in Chronic Gouty Arthritis. Journal of Korean Medical Science, 31(3), 435–442. doi: 10.3346/jkms.2016.31.3.435
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2016.31.3.435
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33292
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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