Subcorneal pustular dermatosis is a pustular eruption that shows subcorneal pustules containing polymorphonuclear
leukocytes and chronic progression. It most commonly affects the trunk, inguinal region, and axilla of middle-aged
women, and the pustules are distributed bilaterally. Cultures of the pustules consistently do not reveal bacterial
growth. Subcorneal pustular dermatosis rarely happens, and no specific etiology and pathogenesis are known. Thus,
we present this case to provide dermatologists with information on its adequate diagnosis and treatment and to
inform them of the risk of subcorneal pustular dermatosis in kidney dialysis patients who use darbepoetin-α.