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심근관류 SPECT에서 가역적인 병변을 보인 환자의 3차원 심장 SPECT/CTA 퓨전영상의 유용성

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Affiliated Author(s)
원경숙
Alternative Author(s)
Won, Kyoung Sook
Journal Title
Nuclear Medicine and Molecular Imaging
ISSN
1869-3474
Issued Date
2009
Keyword
SPECTSPECT/CTfusion imagingcoronary artery disease
Abstract
Purpose: Integration of the functional information of myocardial perfusion SPECT (MPS) and the morpho- anatomical information of coronary CT angiography (CTA) may provide useful additional diagnostic information of the spatial relationship between perfusion defects and coronary stenosis. We studied to know the added value of three dimensional cardiac SPECT/CTA fusion imaging (fusion image) by comparing between fusion image and MPS. Materials and Methods: Forty-eight patients (M:F=26:22, Age: 63.3¡¾10.4 years) with a reversible perfusion defect on MPS (adenosine stress/rest SPECT with Tc-99m sestamibi or tetrofosmin) and CTA were included. Fusion images were molded and compared with the findings from the MPS. Invasive coronary angiography served as a reference standard for fusion image and MPS. Results: Total 144 coronary arteries in 48 patients were analyzed; Fusion image yielded the sensitivity, specificity, negative and positive predictive value for the detection of hemodynamically significant stenosis per coronary artery 82.5%, 79.3%, 76.7% and 84.6%, respectively. Respective values for the MPS were 68.8%, 70.7%, 62.1% and 76.4%. And fusion image also could detect more multi-vessel disease. Conclusion: Fused three dimensional volume-rendered SPECT/CTA imaging provides intuitive convincing information about hemodynamic relevant lesion and could improved diagnostic accuracy.

Keyword SPECT, SPECT/CT, fusion imaging, coronary artery disease
Alternative Title
Added Value of 3D Cardiac SPECT/CTA Fusion Imaging in Patients with Reversible Perfusion Defect on Myocardial Perfusion SPECT
Department
Dept. of Nuclear Medicine (핵의학)
Publisher
School of Medicine
Citation
이병일 et al. (2009). 심근관류 SPECT에서 가역적인 병변을 보인 환자의 3차원 심장 SPECT/CTA 퓨전영상의 유용성. Nuclear Medicine and Molecular Imaging, 43(6), 513–518.
Type
Article
ISSN
1869-3474
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33571
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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