Body Mass Index and Mortality in Korean Intensive Care Units: A Prospective Multicenter Cohort Study

Authors
So Yeon Lim, Won-Il ChoiKyeongman JeonEliseo GuallarYounsuck KohChae-Man LimShin Ok KohSungwon NaYoung-Joo LeeSeok Chan KimIck Hee KimJe Hyeong KimJae Yeol KimJaemin LimChin Kook RheeSunghoon ParkHo Cheol KimJin Hwa LeeJisook ParkGee Young Suh
Department
Dept. of Internal Medicine (내과학)
Issue Date
2014
Citation
PLoS One, Vol.9(4) : e90039-e90039, 2014
ISSN
1932-6203
Abstract
Background The level of body mass index (BMI) that is associated with the lowest mortality in critically ill patients in Asian populations is uncertain. We aimed to examine the association of BMI with hospital mortality in critically ill patients in Korea. Methods We conducted a prospective multicenter cohort study of 3,655 critically ill patients in 22 intensive care units (ICUs) in Korea. BMI was categorized into five groups: <18.5, 18.5 to 22.9, 23.0 to 24.9 (the reference category), 25.0 to 29.9, and ≥30.0 kg/m2. Results The median BMI was 22.6 (IQR 20.3 to 25.1). The percentages of patients with BMI<18.5, 18.5 to 22.9, 23.0 to 24.9, 25.0 to 29.9, and ≥30.0 were 12, 42.3, 19.9, 22.4, and 3.3%, respectively. The Cox-proportional hazard ratios with exact partial likelihood to handle tied failures for hospital mortality comparing the BMI categories <18.5, 18.5 to 22.9, 25.0 to 29.9, and ≥30.0 with the reference category were 1.13 (0.88 to 1.44), 1.03 (0.84 to 1.26), 0.96 (0.76 to 1.22), and 0.68 (0.43 to 1.08), respectively, with a highly significant test for trend (p = 0.02). Conclusions A graded inverse association between BMI and hospital mortality with a strong significant trend was found in critically ill patients in Korea.
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/33684
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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