Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study

Authors
Joo Youn SeoBo Youl ChoiMoran KiHye Lim JangHee Suk ParkHyun Jin SonSi Hyun BaeJin Han KangDae Won JunJin-Woo LeeYoung Jin HongYoung Seok KimChang-Hwi KimU Im ChangJong-Hyun KimHyeon Woong YangHong Soo KimKyeong Bae ParkJae Seok HwangJeong HeoIn Hee KimJung Soo KimGab Jin Cheon
Department
Dept. of Internal Medicine (내과학)
Issue Date
2013
Citation
Journal of Korean Medical Science, Vol.28(6) : 908-914, 2013
ISSN
1011-8934
Abstract
This study aimed to identify the risk factors associated with acute hepatitis A virus (HAV) infection in the Korean population. Participants were recruited from five referral hospitals across the country in 2007 and from 11 hospitals in 2009. Patients with positive anti-HAV IgM antibody tests became the case group, while patients treated for non-contagious diseases at the same hospitals were recruited as controls. A total of 222 and 548 casecontrol pairs were studied in the 2007 and 2009 surveys, respectively. Data from the surveys were analyzed jointly. In a multivariate analysis, sharing the household with HAVinfected family members (OR, 6.32; 95% CI, 1.4-29.6), contact with other HAV-infected individuals (OR, 4.73; 95% CI, 2.4-9.4), overseas travel in 2007 (OR, 19.93; 95% CI, 2.3- 174.4), consumption of raw shellfish (OR, 2.51; 95% CI, 1.8-3.5), drinking bottled water (OR, 1.64; 95% CI, 1.3-8.4), and occupation that involve handling food (OR, 3.30; 95% CI, 1.3-8.4) increased the risk of HAV infection. Avoiding contact with HAV-infected individuals and avoiding raw foods eating could help minimize the risk of hepatitis A infection. Immunization must be beneficial to individuals who handle food ingredients occupationally or travel overseas to HAV-endemic areas.
Keywords
Case-Control StudiesHepatitis AKoreaRisk Factors
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/33792
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
Keimyung Author(s)
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