Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study

Joo Youn SeoBo Youl ChoiMoran KiHye Lim JangHee Suk ParkHyun Jin SonSi Hyun BaeJin Han KangDae Won JunJin-Woo LeeYoung Jin HongYoung Seok KimChang-Hwi KimU Im ChangJong-Hyun KimHyeon Woong YangHong Soo KimKyeong Bae ParkJae Seok HwangJeong HeoIn Hee KimJung Soo KimGab Jin Cheon
Dept. of Internal Medicine (내과학)
Issue Date
Journal of Korean Medical Science, Vol.28(6) : 908-914, 2013
This study aimed to identify the risk factors associated with acute hepatitis A virus (HAV) infection in the Korean population. Participants were recruited from five referral hospitals across the country in 2007 and from 11 hospitals in 2009. Patients with positive anti-HAV IgM antibody tests became the case group, while patients treated for non-contagious diseases at the same hospitals were recruited as controls. A total of 222 and 548 casecontrol pairs were studied in the 2007 and 2009 surveys, respectively. Data from the surveys were analyzed jointly. In a multivariate analysis, sharing the household with HAVinfected family members (OR, 6.32; 95% CI, 1.4-29.6), contact with other HAV-infected individuals (OR, 4.73; 95% CI, 2.4-9.4), overseas travel in 2007 (OR, 19.93; 95% CI, 2.3- 174.4), consumption of raw shellfish (OR, 2.51; 95% CI, 1.8-3.5), drinking bottled water (OR, 1.64; 95% CI, 1.3-8.4), and occupation that involve handling food (OR, 3.30; 95% CI, 1.3-8.4) increased the risk of HAV infection. Avoiding contact with HAV-infected individuals and avoiding raw foods eating could help minimize the risk of hepatitis A infection. Immunization must be beneficial to individuals who handle food ingredients occupationally or travel overseas to HAV-endemic areas.
Case-Control StudiesHepatitis AKoreaRisk Factors
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1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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