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Risk Factors between Patients with Lone and Non-Lone Atrial Fibrillation

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Affiliated Author(s)
김윤년
Alternative Author(s)
Kim, Yoon Nyun
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934
Issued Date
2013
Keyword
Lone Atrial FibrillationRisk Factors
Abstract
Clinical factors such as tall stature, lean body mass, obstructive sleep apnea, alcohol or
caffeine, smoking, endurance sports, and genetic factors are proposed as risk factors for
lone atrial fibrillation (LAF). The KORAF (KORean Atrial Fibrillation) study is a retrospective
multicenter registry that enrolled 3,570 consecutive atrial fibrillation (AF) patients. Data on
risk factors were available for 2,133 patients, of whom 398 (18.7%) were identified as
having LAF. In univariate analysis, patients with LAF were more likely to be men (82.4% vs
59.8%, P < 0.001) and current smokers (25.9% vs 15.6%, P < 0.01), alcohol drinkers
(55.3% vs 31.2%, P < 0.01) and frequent consumers of caffeinated beverages ( > 2 cups/
day) (31.7% vs 19.3%, P < 0.01), and have a family history of AF (9.0% vs 2.6%,
P < 0.001) than the non-LAF patients. Multivariate analysis showed that male gender (OR,
2.30; 95% CI, 1.61-3.27, P < 0.01), family history of AF (OR, 3.12; 95% CI, 1.91-5.12,
P < 0.01), current alcohol use (OR, 2.01; 95% CI, 1.46-2.76, P < 0.01), and frequent
caffeinated beverage consumption (OR, 1.66; 95% CI, 1.20-2.29, P < 0.01) were
independently associated with LAF. In Korean patients, LAF is more closely associated with
male gender, family history of AF, current alcohol and frequent caffeinated beverage
consumption than non-LAF.
Department
Dept. of Internal Medicine (내과학)
Publisher
School of Medicine
Citation
Sung Ho Lee et al. (2013). Risk Factors between Patients with Lone and Non-Lone Atrial Fibrillation. Journal of Korean Medical Science, 28(8), 1174–1180. doi: 10.3346/jkms.2013.28.8.1174
Type
Article
ISSN
1011-8934
DOI
10.3346/jkms.2013.28.8.1174
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/33808
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
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