Localized Muscular Mucormycosis in a Child with Acute Leukemia
- Affiliated Author(s)
- 강진무; 김흥식; 송광순; 이희정; 권건영
- Alternative Author(s)
- Kang, Chin Moo; Kim, Heung Sik; Song, Kwang Soon; Lee, Hee Jung; Kwon, Kun Young
- Journal Title
- Japanese Journal of clinical Oncology
- ISSN
- 0368-2811
- Issued Date
- 1997
- Keyword
- Mucormycosis; Muscle; Leukemia; childhood
- Abstract
- Mucormycosis is a rare fungal infection of childhood, occuring mainly in patients with
chronic illnesses such as diabetes and malignancies. The fungus seldom grows in culture
and confirmation of the diagnosis depends on histologic examination of infected tissues.
To date, the reported natural history of the disease has been rapid progression and a fatal
outcome. Therefore, the importance of early diagnosis by tissue biopsy and early
treatment with surgical debridement and systemic antifungal therapy cannot be
overemphasized. The pulmonary system is the most common site for mucormycosis in
patients with leukemia. We report what we believe to be the first successfully treated case
of isolated muscular mucormycosis occurring in a child with biphenotypic acute leukemia.
The diagnosis was made promptly by tissue examination at the time of surgical
debridement. The patient was also given systemic amphotericin-B therapy.
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