Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

Chi-Min ParkYounsuck KohKyeongman JeonSungwon NaChae-Man LimWon-Il ChoiYoung-Joo LeeSeok Chan KimGyu Rak ChonJe Hyeong KimJae Yeol KimJaemin LimChin Kook RheeSunghoon ParkHo Cheol KimJin Hwa LeeJi Hyun LeeJisook ParkJuhee ChoShin Ok KohGee Young Suh
Dept. of Internal Medicine (내과학)
Issue Date
Journal of Critical Care, Vol.29(3) : 409-413, 2014
Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.
PrognosisPerformance statusIntensive careHospital mortality
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