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Comparison between Initial and Recent Surgical Outcome of 15-Year Series of Surgically Remediable Epilepsy

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Affiliated Author(s)
손은익
Alternative Author(s)
Son, Eun Ik
Journal Title
Journal of Korean Neurosurgical Society
ISSN
2005-3711
Issued Date
2010
Keyword
EpilepsySurgeryTreatmentOutcome
Abstract
Objective : The aim of this study is to compare the surgical outcome of the initial and recent surgical cases, during our 15-years experience, in
terms of the surgical strategies and the prognostic factors for surgically remediable epilepsy.
Methods : We retrospectively reviewed and compared the surgical outcomes between the initial 256 (Group I) and recent 139 (Group II) patients
according to the time period of operation for a total of 518 consecutive epilepsy surgeries at our institution since 1992. The patients of the middle
intermediate period, which were subjected to changed surgical strategies, were excluded.
Results : The surgical outcome data from the initial and recent groups showed a much improved outcome for patients who underwent temporal
lobe epilepsy (TLE) surgery over time. The number of patients with a good outcome (Engel class I-II) was much increased from 87.7% (178 TLE
cases of Group I) to 94.8% (79 TLE cases of Group II) and this was statistically significant (p = 0.0324) on univariate analysis. Other remarkable
changes were the decreased performance of intracranial invasive studies from 43.5% in Group I to 30.9% in Group II due to the advanced neuroimaging
tools. The strip/grid ratio was reduced from 131/32 in Group I to 17/25 in Group II, because of a markedly reduced mesial TLE surgery and
an increased extratemporal epilepsy surgery.
Conclusion : Our results show that surgical outcome of epilepsy surgery has improved over time and it has shown to be efficient to control
medically intractable epilepsy. Appropriate patient selection, comprehensive preoperative assessments and more extensive resection are
associated with good postoperative outcomes.
Department
Dept. of Neurosurgery (신경외과학)
Publisher
School of Medicine
Citation
Myoung-Hee Lee and Eun-Ik Son. (2010). Comparison between Initial and Recent Surgical Outcome of 15-Year Series of Surgically Remediable Epilepsy. Journal of Korean Neurosurgical Society, 48(3), 230–235. doi: 10.3340/jkns.2010.48.3.230
Type
Article
ISSN
2005-3711
DOI
10.3340/jkns.2010.48.3.230
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34138
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학)
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