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A Propensity Score-Matched Case-Control Comparative Study of Laparoscopic and Open Liver Resection for Hepatocellular Carcinoma

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Affiliated Author(s)
안근수강구정김용훈김태석임태진
Alternative Author(s)
Ahn, Keun SooKang, Koo JeongKim, Yong HoonKim, Tae SeokLim, Tae Jin
Journal Title
Journal of Laparoendoscopic & Advanced Surgical Techniques
ISSN
1092-6429
Issued Date
2014
Abstract
Background: The aim of this study was to compare the perioperative and long-term oncologic outcomes of
laparoscopic liver resection (LLR) and open liver resection (OLR) for single hepatocellular carcinoma (HCC) in
case-controlled patient groups using the propensity score.
Patients and Methods: Between January 2005 and February 2013, 292 patients underwent surgical resection for
HCC. Of these, 202 patients who underwent surgical resection for initial treatment for a single mass were enrolled.
These patients were divided into two groups according to the method of operation: the Lap group (patients who
underwent LLR) and the Open group (patients who underwent OLR). To correct different demographic and
clinical factors in the two groups, propensity score matching was used at a 1:1 ratio, and, finally, 102 patients were
enrolled in this study, 51 patients in each group. Preoperative characteristics, perioperative results, and long-term
results were retrospectively analyzed based on the prospectively recorded database.
Results: Preoperative baseline variables were well balanced in both groups. There were no differences of extent
of surgery and rate of anatomical resection between the two groups. With the exception of a shorter postoperative
hospital stay in the Lap group than that of the Open group (8.2 days versus 12.3 days; P = .004), there
were no significant differences in perioperative, pathological, and long-term outcomes. The 5-year overall
survival rates were 80.1% in the Lap group and 85.7% in the Open group, respectively (P = .173). The 5-year
disease-free survival rates were 67.8% in the Lap group and 54.8% in the Open group, respectively (P = .519).
Conclusions: LLR for HCC is safe, and long-term oncologic outcomes in selected patients were comparable to
those who underwent OLR.
Department
Dept. of Surgery (외과학)
Publisher
School of Medicine
Citation
Keun Soo Ahn et al. (2014). A Propensity Score-Matched Case-Control Comparative
Study of Laparoscopic and Open Liver Resection
for Hepatocellular Carcinoma. Journal of Laparoendoscopic & Advanced Surgical Techniques, 24(12), 872–877. doi: 10.1089/lap.2014.0273
Type
Article
ISSN
1092-6429
DOI
10.1089/lap.2014.0273
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34150
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Surgery (외과학)
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