A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue

Authors
Young Kook ShinJoong Goo KwonKa Young KimJae Bum ParkSeok Jae HanJong Woon CheonEun Young KimHo Gak KimTae Sung LeeKyung Sik ParkKyoung Sook Won
Department
Dept. of Internal Medicine (내과학); Dept. of Nuclear Medicine (핵의학)
Issue Date
2010
Citation
Journal of Neurogastroenterology and motility, Vol.16(1) : 77-82, 2010
ISSN
2093-0879
Abstract
Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual period. Here, we report a case of cyclic vomiting syndrome in adult patient characterized by stereotypical vomiting attack, occurring in every menstruation period. Recurrent vomiting episodes began 6 years ago and we treated this patient with subcutaneous injection of goserelin, a gonadotropin-releasing hormone analogue (GnRHa) and oral estrogen. After 4 months of therapy, she was symptom free for the following 5 years, even with the resumed normal menstruation. Recurrence of vom - iting attack with same pattern occurred 1 month before readmission. Treatment with intravenous lorazepam aborted vomiting, but could not prevent recurrences of vomiting and epigastric pain. We treated the patient with GnRHa and oral estradiol again which effectively prevented recurrence of the symptoms.
Keywords
Cyclic vomiting syndromeMenstrual periodGonodotropin-releasing hormone analogue
URI
http://kumel.medlib.dsmc.or.kr/handle/2015.oak/34177
Appears in Collections:
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. Journal Papers (연구논문) > 1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
Keimyung Author(s)
박경식; 원경숙
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