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A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue

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Affiliated Author(s)
박경식원경숙
Alternative Author(s)
Park, Kyung SikWon, Kyoung Sook
Journal Title
Journal of Neurogastroenterology and motility
ISSN
2093-0879
Issued Date
2010
Keyword
Cyclic vomiting syndromeMenstrual periodGonodotropin-releasing hormone analogue
Abstract
Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed
with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual
period. Here, we report a case of cyclic vomiting syndrome in adult patient characterized by stereotypical vomiting attack,
occurring in every menstruation period. Recurrent vomiting episodes began 6 years ago and we treated this patient with
subcutaneous injection of goserelin, a gonadotropin-releasing hormone analogue (GnRHa) and oral estrogen. After 4 months
of therapy, she was symptom free for the following 5 years, even with the resumed normal menstruation. Recurrence of vom -
iting attack with same pattern occurred 1 month before readmission. Treatment with intravenous lorazepam aborted vomiting,
but could not prevent recurrences of vomiting and epigastric pain. We treated the patient with GnRHa and oral estradiol
again which effectively prevented recurrence of the symptoms.
Department
Dept. of Internal Medicine (내과학)
Dept. of Nuclear Medicine (핵의학)
Publisher
School of Medicine
Citation
Young Kook Shin et al. (2010). A Case of Cyclic Vomiting Syndrome Responding to Gonadotropin-Releasing Hormone Analogue. Journal of Neurogastroenterology and motility, 16(1), 77–82. doi: 10.5056/jnm.2010.16.1.77
Type
Article
ISSN
2093-0879
DOI
10.5056/jnm.2010.16.1.77
URI
https://kumel.medlib.dsmc.or.kr/handle/2015.oak/34177
Appears in Collections:
1. School of Medicine (의과대학) > Dept. of Internal Medicine (내과학)
1. School of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학)
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