Reversible orthostatic hypotension in PICA territory cerebellar infarction
- Affiliated Author(s)
- 이형; 김현아
- Alternative Author(s)
- Lee, Hyung; Kim, Hyun Ah
- Journal Title
- Journal of the Neurological Sciences
- ISSN
- 0022-510X
- Issued Date
- 2014
- Abstract
- Impaired sympathetic vasoconstriction reflex of muscle and splanchnic vessels in response to orthostatic stress can cause orthostatic hypotension [1]. Orthostatic hypotension was reported in focal central nervous system lesions involving the brainstem or spinal cord [2,3]. The cerebellum has also been reported to participate in regulating blood pressure (BP) by modulation of vestibulo-sympathetic responses [4–7]. However, most of the studies [4–7] on the role of cerebellum in regulating BP were based on the results of an experimental animal model. The cardiovascular response during orthostasis after a cerebellar lesion remains uncertain in humans. Moreover, there are no reports on the influence of cerebellar infarction on cardiovascular control according to a positional change in humans. We examined a patient with a cerebellar infarction who had orthostatic dizziness after vertigo subsided and who also showed orthostatic hypotension during a head-up tilt test.
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